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Author Topic: Moroccan Neolithic paper finally out
capra
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www.pnas.org/content/early/2018/06/11/1800851115

Ancient genomes from North Africa evidence prehistoric migrations to the Maghreb from both the Levant and Europe

quote:
The extent to which prehistoric migrations of farmers influenced the genetic pool of western North Africans remains unclear. Archaeological evidence suggests that the Neolithization process may have happened through the adoption of innovations by local Epipaleolithic communities or by demic diffusion from the Eastern Mediterranean shores or Iberia. Here, we present an analysis of individuals’ genome sequences from Early and Late Neolithic sites in Morocco and from Early Neolithic individuals from southern Iberia. We show that Early Neolithic Moroccans (∼5,000 BCE) are similar to Later Stone Age individuals from the same region and possess an endemic element retained in present-day Maghrebi populations, confirming a long-term genetic continuity in the region. This scenario is consistent with Early Neolithic traditions in North Africa deriving from Epipaleolithic communities that adopted certain agricultural techniques from neighboring populations. Among Eurasian ancient populations, Early Neolithic Moroccans are distantly related to Levantine Natufian hunter-gatherers (∼9,000 BCE) and Pre-Pottery Neolithic farmers (∼6,500 BCE). Late Neolithic (∼3,000 BCE) Moroccans, in contrast, share an Iberian component, supporting theories of trans-Gibraltar gene flow and indicating that Neolithization of North Africa involved both the movement of ideas and people. Lastly, the southern Iberian Early Neolithic samples share the same genetic composition as the Cardial Mediterranean Neolithic culture that reached Iberia ∼5,500 BCE. The cultural and genetic similarities between Iberian and North African Neolithic traditions further reinforce the model of an Iberian migration into the Maghreb.
Haven't read it yet, but sounds like they've incorporated the Taforalt data. Hopefully the genomes have been released too.
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the lioness,
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Elmaestro
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...So IAM are essentially show continuity from the Taforalt?

IDeK what I'm looking at anymore

 -

KEB is Identical to IAM, IAM is just slightly less west african than taf???
EDIT: The chart is apparently shifted downwards... KEB actually lacks Hadza component, has a reduced Red-SSA component and increased anatolian.

quote:
West Eurasian populations can be modeled as the admixture
of four different ancestral components (2): Eastern and Western
European hunter-gatherer and Iranian and Levantine Neolithic.
We explored the placement of Moroccan and Southern Iberian
Neolithic samples in this context and compared their genetic
affinities to ancient and present-day West Eurasian and Levant
populations in the Human Origins panel, as well as to other
available aDNA population data. Interestingly, PCA revealed
that IAM individuals are similar to North African Later Stone
Age samples from the Taforalt site in Morocco, dated ∼15,000 y
ago (Fig. 2 and SI Appendix, Supplementary Note 6). When projected,
IAM samples are halfway between Taforalt and modern
North Africans, in the Levantine corner of the PCA space (Fig. 2).

Southern Iberian Neolithic individuals from TOR cluster with
Sardinians and with other Anatolian and European Neolithic
samples. Moreover, KEB samples are placed halfway between the
IAM and Anatolian/European farmer clusters, in close proximity
to Levant aDNA samples and also to Guanche samples (16) (from
the indigenous population of the Canary Islands known to have a
Berber origin; ref. 23). When compared using ADMIXTURE (SI
Appendix, Supplementary Note 7), IAM samples possess ∼100% of
a component partially shared by aDNA samples from the Levant
(Fig. 2). This IAM-like component is observed mainly in modern
North African individuals, following a west-to-east cline, and in
the Guanches. Interestingly, the Early Neolithic individuals from
Iberia form a different cluster from the Anatolian, Aegean, and
European Early Neolithic samples, sharing their main component
with Middle Neolithic/Chalcolithic samples. Lastly, KEB can be
explained as having both IAM-like and Iberian Early Neolithic
components (Fig. 2). The same admixture profile is observed in
the Guanche samples, but the amount of IAM ancestry is consistently
higher in all of the samples. Given that the Guanches
could have originated in a different area of the Maghreb, this
result might suggest that the European Neolithic impact in North
Africa was heterogeneous.


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the lioness,
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^ I see Taforalt mentioned there, is that the Supplement or published journal version? Didn't see that in Pre-print
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Elmaestro
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Published version
...Your copy and paste was once again unnecessary as the preprint have been discussed and posted before by the OP lol...

However now that you mention supp...

I must say... that there's some shit in there...
http://www.pnas.org/content/pnas/suppl/2018/06/11/1800851115.DCSupplemental/pnas.1800851115.sapp.pdf

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the lioness,
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(as if you didn't "copy and paste")

{pre-preint text post deleted]

Also the only time the pre-print article was mentioned in ES before was
in this thread

http://www.egyptsearch.com/forums/ultimatebb.cgi?ubb=get_topic;f=8;t=009830;p=1


IAM population, Natufians, Proto-Semitic, North African Component

_______________________

Clyde posted the link on page 1 with his comment and a very brief comment by xyyman on page 2,
not much discussion

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the lioness,
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Pre-print version vs. published

Pre-print

quote:

Interestingly, PCA reveals that IAM individuals are different from any aDNA sample studied to date (Figure 2; Supplementary Note 6). When projected, IAM samples are close to modern North Africans, in the Levantine corner of the PCA space (Figure 2). Southern Iberian Neolithic individuals from TOR cluster with Sardinians and with other Anatolian and European Neolithic samples. Moreover, KEB samples are placed halfway between the IAM and Anatolian/European farmer clusters, in close proximity to Levant aDNA samples and also to Guanche samples16, the indigenous population of the Canary Islands known to have a Berber origin


Published


quote:
Originally posted by Elmaestro:

Interestingly, PCA revealed that IAM individuals are similar to North African Later Stone
Age samples from the Taforalt site in Morocco, dated ∼15,000 y
ago (Fig. 2 and SI Appendix, Supplementary Note 6). When projected,
IAM samples are halfway between Taforalt and modern
North Africans, in the Levantine corner of the PCA space (Fig. 2).

Southern Iberian Neolithic individuals from TOR cluster with
Sardinians and with other Anatolian and European Neolithic
samples. Moreover, KEB samples are placed halfway between the
IAM and Anatolian/European farmer clusters, in close proximity
to Levant aDNA samples and also to Guanche samples (16) (from
the indigenous population of the Canary Islands known to have a
Berber origin; ref. 23). When compared using ADMIXTURE (SI
Appendix, Supplementary Note 7), IAM samples possess ∼100% of
a component partially shared by aDNA samples from the Levant
(Fig. 2). This IAM-like component is observed mainly in modern
North African individuals, following a west-to-east cline, and in
the Guanches.

This seems to show a significant correction in a pre-print to published version, something to be aware of in this pre-print versions
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Elmaestro
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 -

Anyone remember when that boy Polako(ithink thats how you spell it) Said the taf was replaced by the IAM who are incoming neolithic population from the Near east lmaooo..

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the lioness,
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People new to this forum are not going to be able to follow all these abbreviations that people constantly use "IAM" etc

aka "Early Neolithic Moroccans"

"IAM" is not a standard term like to an extent "EEF" has become.
It is an abbreviation of an particular arabic place name in Morocco, Ifri N'Ammar

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Elmaestro
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^Why don't you bring it all in with a comprehensive post.

I realized that there is a complete tonal shift in how the authors are describing the IAM. lol. No more of that "closest to the near east" bullshit.. They actually point out that Horners are the closest to the IAM. The Fst scores look like I expected them to, however I must admit I am surprised that he IAM are that close to Taforalt.

Still tryna find the link to the genomes

---

They added f4 problems to actually look for SSA correspondence this time around ..I wonder if someone got around to critiquing the preprint. Cuz now, wala, there's heavy west African signals all of a sudden.
 -


Sidenote* Gambians seems to show the strongest signals... as opposed to YRI

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the lioness,
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topic artcile:
"When projected,
IAM samples are halfway between Taforalt and modern
North Africans,"



wikipedia:

Taforalt individuals belonged to mtDNA haplogroups U6a and M1b. Y-DNA analysis shows that the Taforalt males all belonged to Y-DNA haplogroup E1b1b1a1 (M78), which is closely related to the E1b1b1b (M123) subhaplogroup that has been observed in skeletal remains belonging to the Epipaleolithic Natufian and Pre-Pottery Neolithic cultures of the Levant.

______________________


E-M78 is widely distributed in North Africa, Horn of Africa, West Asia (stretching as far as Southern Asia), and Europe.[2][6]

The most basal and rare E-M78* paragroup has been found at its highest frequencies in Egyptians from the Gurna Oasis (5.88%), with lower frequencies also observed in Moroccan Arabs, Sardinians, the Balkans, and Andalusians from Huelva.[2][3][12]

The highest frequencies of all the defined E-M78 sub-clades is primarily found amongst Afroasiatic-speaking populations in the large area stretching from the haplogroup's putative place of origin in Upper Egypt to the Sudan and the Horn of Africa

________________________________________


Could the YDNA of the Taforalt originate in Egypt ????

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Forty2Tribes
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quote:
Originally posted by Elmaestro:

I realized that there is a complete tonal shift in how the authors are describing the IAM. lol. No more of that "closest to the near east" bullshit.. They actually point out that Horners are the closest to the IAM. The Fst scores look like I expected them to, however I must admit I am surprised that he IAM are that close to Taforalt.

Where are you seeing this? I see the old language
https://www.biorxiv.org/content/biorxiv/early/2018/02/20/191569.full.pdf

quote:
This suggests that most of IAM ancestry originates from an out-of-Africa source, as IAM
217 shares more alleles with Levantines than with any sub-Saharan Africans, including the
peer-reviewed) is the author/funder. It is made available under a CC-BY-NC-ND 4.0 International license.
bioRxiv preprint first posted online Sep. 21, 2017; doi: http://dx.doi.org/10.1101/191569. The copyright holder for this preprint (which was not
10
4,500-year-old genome from Ethiopia14

Serious logical fallacy to compare that many populations to MOTA.

Edit Nevamind I see it [Big Grin]

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Elmaestro
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^there's one link in the op and I posted the supp above.
the study has been peer reviewed and published...
the preprint has become obsolete ..let it die.

Study OP
Supp

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Forty2Tribes
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quote:
Originally posted by Elmaestro:
^there's one link in the op and I posted the supp above.
the study has been peer reviewed and published...
the preprint has become obsolete ..let it die.

Study OP
Supp

But Maestro its such a great model for ethnocentric bias.
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Qward
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Thanks for the links to the study.
Here's my attempt to make the first image Elmaestro posted clearer.

 -

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Clyde Winters
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quote:
Originally posted by Fourty2Tribes:
quote:
Originally posted by Elmaestro:
^there's one link in the op and I posted the supp above.
the study has been peer reviewed and published...
the preprint has become obsolete ..let it die.

Study OP
Supp

But Maestro its such a great model for ethnocentric bias.
Not only ethnocentric bias, it is a lie. There is no archaeological data supporting a back migration. All the evidence points to Africans carry culture into Iberia, the steppes and etc. I discuss this material in my recent paper Y-CHROMOSOME R1 WAS INTRODUCED TO EURASIA BY KUSHITES web page. It is sad that Geneticist perpetuate lies to manufacture a European influence over history that they never had, so as to promote white Supremacy.

--------------------
C. A. Winters

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xyyman
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Originally posted by Elmaestro:
[Q] Look, being met with resistance because I'm a black researcher by "euro-clowns" or whatever is one thing, however it's the fucking subservient Africans (diasporans) who irritate me. It's only common that you'll have to deal with logical loopholes, and mental gymnastics from the former, I don't care if they chose to understand where I'm coming from or not. The signs are clear regarding certain things it's only the fine details that need to be ironed out.

The mighty question is what does anyone have to gain by denying the "Africanity" of certain protocultures?

It seems quite obvious for me that the ancient African Genetic landscape was very broad. The problem stemmed from sloppy partitioning of Subsaharan Africans in the first place. Look at the ancient Ballito Bay specimen for example and keep in the back of our minds the genetic Diversity of Africans.

-Ballito Bay A and Yoruba have a distance (FST) of ~0.150... YRI have ancestry from a population that diverged earlier than Balito bay did.
-Natufians actually have IAM(like) Admixture and have a distance of ~0.200 from them!!?!
-The Bantu expansion seen every corner of the African continent...that's shared ancestry dating to roughly 4kya max, yet the Luhya and Yoruba avg differences can clear a the distance of the entirety of Europe.
-And Natufians and Yoruba have an average distance of 0.168 (FST) - over 15% closer than a population with shared affinity to Natufians (IAM)

So all in all... WTF is a Eurasian and WTF is a SSA? I thought it would be wise to give Eurasian a definition, basically; Eurasian is a Geo-temporal place holder for the extreme levels of drift apparently separating modern non African and African populations. ("Subsaharan African" was is and will always be a misnomer.) The further we reach back for samples in Africa AND the Near East the more the previous boundaries get muddy so we find ourselves using modern genetic substructure to Identify Ancient populations... some people refuse to see the issue in doing so, This is just one example of why Genetics, especially of only a handful of ancient individuals, can NOT possibly be the end all answer to anything....cuz, for example, Yorubans and Natufians could share Ancient ancestry that parallels IAM and we wouldn't even know...

This is why conceding an indigenous North African component is unacceptable. Jebel ihroud, MtHap L3* and schlebusch's qpGraphs (and the ones that follow) is a nightmare to the "Anti-Afrocentric." [/Q][/QUOTE]

----------------

From Beyoku
After taking a hiatus from Egyptsearch and having a presence in multiple forums over the years this is my diagnosis of what is going on in the anthroscene. I will list the main 3 issues tha come top mind and they are NOT unique among people of NOT of African descent.

1 - Its not what you are saying....its the fact that you (Black folks/White folks) have the audacity to say it..

2 - The are coming to the realization....and quite begrudgingly that the concept "All humans are African" is not so much as an Abstract but rather a recent genetic reality.
. It will be damaging to peoples fragile psyche to see Ancient African DNA - PRIOR to the standard OOA already carrying "Eurasian" components. XYYMAN gets the props for this early conclusion although his evidence sucked. This leads to anther point, the "The Eurasian Shell Game".

3 - Well what you could do is play a game with the term "Eurasian". It helps them sleep better at night. That is it for now. This is why Natufian cannot be partly African regardless of proximity to Africa and E1b1b. This is why ancient remains from North Africa IAM etc have no African ancestry despite U6,M1,E1b1b autosomal sharing with Yoruba.


see my thread on ESR. We are all Africans...

Guido Barbujani: "We’re all African"
The renowned Italian geneticist will give a conference on 28 October as part of the “Evolution and Culture” series of lectures organized by B•Debate and the CCCB.

--------------------
Without data you are just another person with an opinion - Deming

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xyyman
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quote by Dr Winters.


"It is sad that Geneticist perpetuate lies to manufacture a European influence over history that they never had, so as to promote white Supremacy."

http://www.egyptsearch.com/forums/ultimatebb.cgi?ubb=get_topic;f=8;t=009974

Europeans in the 1800's had become invested in their premise to remain dominant. They have a vested interest to lie.

quote:
Originally posted by xyyman:
 -



--------------------
Without data you are just another person with an opinion - Deming

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1. So Taforalt, IAM and ……KEB carry both West African and Hadza components in UNSUPERVISED analysis. KEB carry lower amounts.
2. Confirmation that these populations(Taforalt and IAM) with large amounts of SSA ancestry were black skinned. KEB carried “some” derived SNPs for pigmentation. We also know that SLC24A5 derived was in Southern Africa maybe 19000BC. Amazes me these researchers don’t read each other’s work!!!!!!!!
3. ElMaestro can you confirm TOR do not have any SSA ancestry? I don’t believe it. It is impossible for Toforalt to have SSA ancestry and TOR less than 100miles away do not have it.

But we know La Brana who lived right next door to TOR was also black skinned. Tic! Toc! Connect the dots!


And what do they mean by "heterogenous"?

------
Quotes:
result might suggest that the European Neolithic impact in North Africa was **heterogeneous**???.
Recent aDNA analysis of Moroccan Later Stone Age samples from the Taforalt site indicates that at least one-third of Taforalt
ancestry derives from sub-Saharan African populations
. When Taforalt and sub-Saharan African samples are included in the
***UNSUPERVISED*** clustering analysis (SI Appendix, Supplementary Note 7), we observe that IAM and Taforalt cluster together at K = 7, as
observed for the MEGA-HGDP ADMIXTURE analysis. However, as reported by van de Loosdrecht et al. (17) for Taforalt, we
can detect both West African (maximized in Gambians and Yoruba) and East African (maximized in Hazda) components **in
IAM*** at lower K values
. In contrast, TOR does not show any sub-Saharan African ancestry and KEB is again in an intermediate
position, with lower sub-Saharan African ancestry than IAM.
To compare our samples directly to the genomes of ancient
and modern populations, we calculated pair-wise fixation index (FST) distances, which, unlike PCA and global ancestry analyses,
are insensitive to the inclusion of large numbers of individuals from modern populations. FST values (noted in parentheses) indicate that
the IAM samples are as differentiated from all other populations as Yoruba are from non-Africans (SI Appendix, Supplementary Note 9),
with the exceptions of Taforalt (0.049) and, to a lesser extent, KEB

Lastly, although limited by low coverage, phenotypic predictions based on genetic variants of known effects agree with our estimates
of global ancestry. IAM people did not possess any of the European SNPs associated with light pigmentation, and most likely had
dark skin and eyes. IAM samples contain ancestral alleles for pigmentation-associated variants present in SLC24A5 (rs1426654),
SLC45A2 (rs16891982), and OCA2 (rs1800401 and 12913832) genes
. On the other hand, KEB individuals exhibit some European derived
alleles that predispose individuals to lighter skin and eye color, including those on genes SLC24A5 (rs1426654) and OCA2 (rs1800401) (SI Appendix


ivory and ostrich eggs found in Iberian sites, confirm the existence of contacts and exchange networks through both sides of
the Gibraltar strait at this time. Our analyses strongly support that at least some of the European ancestry observed today in
North Africa is related to prehistoric migrations, and local Berber populations were already admixed with Europeans before
the Roman conquest. Furthermore, additional European/Iberian ancestry could have reached the Maghreb after KEB

--------------------
Without data you are just another person with an opinion - Deming

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So Northern Europeans decided to take a kind of ownership of these ancient civilizations like Greece etc. Which means they decided to control the narrative. Today they create created labels such as “Eurasian” and “non-African” when we know there is no such thing as Eurasian originated DNA.

--------------------
Without data you are just another person with an opinion - Deming

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Swenet
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Which of these WHG samples is WHG only, lioness?

Villabruna (Switzerland HG) has non-WHG
WHG has non-WHG

There is no such thing as a WHG-only sample. Switzerland HG being WHG + Mota doesn't mean other WHG samples don't have something Mota-like also. That was the point I was trying to make in that other thread.

quote:
Originally posted by Qward:
Thanks for the links to the study.
Here's my attempt to make the first image Elmaestro posted clearer.

 -


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 -

--------------------
Without data you are just another person with an opinion - Deming

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the lioness,
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^ priorites
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quote:
Originally posted by the lioness,:
^ priorites

https://s22.postimg.cc/9b9jxpzgx/U6_in_YAM-_African.jpg
 -
IMG Resized //MOD

[ 13. June 2018, 01:53 PM: Message edited by: Elmaestro ]

--------------------
Without data you are just another person with an opinion - Deming

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xyyman
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Quote from the study:
“Haplogroup T2
Samples KEB.7, TOR.6 and TOR.7 are classified as T2b3+151, with no private mutations (See Figure S4.1). T2b, dated ~10,000 years ago, is mainly distributed in Europe. T2b is considered to have dispersed within Europe in early Neolithic times53, a fact that has been confirmed by direct analysis of aDNA”

Quote from wiki…
“The basal haplogroup T* is found among Algerians in Oran (1.67%) and Reguibate Sahrawi (0.93%).[1] It is also distributed among the Soqotri (1.2%).[2]”
mtDNA T is found throughout the horn and further south in the Datoga people of Tanzania

Soqotri
 -

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Elmaestro
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The genomes are being uploaded as we speak,

@Qward Thanks for the edit to the image.

@42tribes You're right, it definitely is... lol... It was super blatant... and almost disrespectful.

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quote:
Originally posted by the lioness,:
^ priorites

Me or gramps? Don't know what you mean..
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the lioness,
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quote:
Originally posted by Swenet:
quote:
Originally posted by the lioness,:
^ priorites

Me or gramps? Don't know what you mean..
comment for xyyman, he was showing his priorities
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xyyman
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where? Link

quote:
Originally posted by Elmaestro:
[Q] The genomes are being uploaded as we speak,

[/Q]



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quote:
Originally posted by xyyman:
where? Link

quote:
Originally posted by Elmaestro:
The genomes are being uploaded as we speak,



Here you go
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capra
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quote:
Originally posted by Elmaestro:
Sidenote* Gambians seems to show the strongest signals... as opposed to YRI

Gambians (and to a lesser extent Mandenka) can be modelled with minor Iberomaurusian (or other North African) admixture in Global25. OTOH Skoglund et al modelled Gambians as 100% Mende with no PPNB (assuming they're the same samples), and in this study's ADMIXTURE they have almost no yellow component (Mandenka have more). Gambians have some E-M35 (including M78 and L19), plus their northern location, I'm guessing they have minor North African ancestry which Yoruba don't. The wild card is the Basal African/West African archaic thing.
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xyyman
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"The wild card is the Basal African/West African archaic thing."

Finally. Now you are catching on.....Took you some time but you got here. HE! HE! He!

But Skoglund had Mende as more ancient than YRI. Containing more archaic admixture.

It would be interesting to pull those archaic AIM from Mende and run it against WHG and ANE!

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For a little African perspective on Taforalt.
Africa, south of a line from Guinea Bissau to
South Sudan to southern Kenya, was inhabitable
through time. Note yellow grasslands, purple
savanna w/trees, and various green scub and
forestry.

2600km/1600m of desert separated Taforalt from
the grasslands to its south for 10000 years. 'SSA'
'elements in Taforalt were there before the Ice Age
began. With the West African Monsoon in full retreat,
no oxen pack-asses transport beasts of burden nor
travel horses or camels, and no water storage,
crossing the vast desert = a 💀 death wish.
There were two other sites along Africa's
south Mediterranean coast though.

Below the desert line's another story. Virtually
a Grasslands Paradise throughout the Ice Ages.
Blombos and Panga ya Saidi are asterisked.
Malawi's Hora Woman lived after the mapped
Maurusian timeframe. Her 6-way African
substructure ancestry could go back to
the West African Monsoon Optimum.


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quote:
Originally posted by capra:
quote:
Originally posted by Elmaestro:
Sidenote* Gambians seems to show the strongest signals... as opposed to YRI

Gambians (and to a lesser extent Mandenka) can be modelled with minor Iberomaurusian (or other North African) admixture in Global25. OTOH Skoglund et al modelled Gambians as 100% Mende with no PPNB (assuming they're the same samples), and in this study's ADMIXTURE they have almost no yellow component (Mandenka have more). Gambians have some E-M35 (including M78 and L19), plus their northern location, I'm guessing they have minor North African ancestry which Yoruba don't. The wild card is the Basal African/West African archaic thing.
I picked up on a lot of this, (with the exception of the Global 25 stuff) There's definately a lot of prehistory masked by both the homogeneity of "OOAs" and the recombination of very divergent ancestry. I was able to squeeze out some wierd admixture signals dating towards the holocene for YRI using the 700yo pemba (one of the eldest W.African-lke specimen)
code:
                Source1;Source2                 amp (Z)                                 time in Generations (z)  
RESULT_1 Mota;Tanzania_Pemba_700BP 0.000154805 +/- 4.81939e-05 (Z=3.21213) 234.581 +/- 45.6366 (Z=5.14019)
RESULT_1 WHG;Tanzania_Pemba_700BP 0.000162835 +/- 5.16218e-05 (Z=3.15438) 234.581 +/- 45.6366 (Z=5.14019)

I was able to see some decent curves when mixing Ancient Near easterners and Taofralt with pemba However the tests failed (Jackknife)

example:
code:
*** Computing 2-ref weighted LD with weights WHG Tanzania_Pemba_700BP ***

analyzing chrom 1 3 2 4 8 7 6 5 12 11 10 9 16 15 20 13 14 19 17 18 21 22

==> Time to run alder: 0.406488

+6.0e-05
|
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| x
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| x x x x
| x x x x xxx
| x
| x x x xx
| x x
| x
| x
| x x x
| x xx x x x x x x
+---------+---x---x-+---------+---------+-----x---+-----x---+---------+--------
| 1 2 3 x 4 5 6 7 cM
| x x x
| x x x x
| x x
| x x xx x x x x x
| x
|
| x x x
|
| x x x
| x
| x
| x

****Successful

*** Computing 2-ref weighted LD with weights Taforalt Tanzania_Pemba_700BP ***

analyzing chrom 1 3 4 2 8 7 6 5 12 11 9 10 16 20 13 15 14 17 19 18 21 22

==> Time to run alder: 0.244233

+9.0e-05
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| x x
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| x x x
| x
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| x x
| x x x x x x x
| x x
| x
| x x x
| x x x x
+---------+---------+---------+------x--+---------+----x----+------x--+--------
| 1 x2 3 4x 5 6 x 7 x xxcM
| x x x
| x x
| xxx x x x x
| x
| x x x x x x x
| x
| x x x
| x
| x
| x
|
| x


******Failed

Pemba_700bp + the following created great curves:
Iran_N (Very Strong) Failed @ p=0.051
Taforalt Failed Jackknife
Levant_N Failed @ p=0.25
Luxmanda (very strong) Failed @ p=0.11
Mota - Success P < 0.025
WHG - Success P < 0.025
_________________________________________________


There's also signs like this

quote:
To follow up on my last post, some d-stats...

Mbuti/South_Africa_2000BP/Chimp Yoruba Mota Bichon
- hhuuuugelly postitive
Mbuti/South_Africa_2000BP/Chimp Mota Yoruba Bichon
- again hugely positive

These two stats suggest either Mota or Yoruba is a mix of two streams of ancestry, a basal one and one closer to the OOA node.

...It's coming together piece by piece. There has to be some consistency with FST scores. No way Taforalt and IAM should be more distant to YRI than Natufian right?

Anywho I got the IAM genomes ready for analysis will fuq around with them later in the day if I can.

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Tukuler
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"No way Taforalt and IAM should be more distant to YRI than Natufian right?"


Oh no. 1600 miles of desert over 10000 years
should be no impediment to northward geneflow
while the tree lined south Mediterranean coast
of Libya and Egypt would hamper Levant <-->
Maghreb geneflow. Riiight.

U6a and M1 hint more of tropical W Africa than
they do to the far NE extension of Africa, E-M35
too. << cough cough >>


However, Fregel's HOD PCA S6.3 does plot Taforalt
as closer to SSA than to Natufian which overlays
Neolithic Iran and is overlayed by KEB. Taforalt
is closer to Luxmanda than it is to Natufian.
Pemba is 3X farther away from Taforalt than
Luxmanda is. Consider the relative worth
of PCA vs other analytic tools.

Fregel, or the printer, did a great disservice
hiding Africans out of Fig S7.6 while captioning
they are included in the aDNA ADMIXTURE plot. Tsk,
tsk.

I find Fig S7.7 incredible, seeing no difference
in Yoruba and Xuun nor distinguishing Sandawe
from Oromo, Mbuti from Mende???

Is Fregel hiding something?

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How did I miss this? The yellow component is North African ancestry isn't it? It only peaks in North African(IAM, Taf) groups.

And if I am reading this right thks really creates trouble for those who believe post-Ateria North Africa was largely contructed by foreign backmigration.

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@Tukuler, the whole graph is a disservice,
1. The names aren't aligned at all. The whole block that seemingly includes Wambo, xuun etc. are all actually Yoruba.
2. fig S7.6 and 7.7 are from the same run.

@Elite Diasporan
Bruh the whole "debate" on ABF a year ago for example, regarding NA ancestry was a waste of time.
There was a time when we warned people how ancient N.Africans will plot in PCA

I remember trying to explain the phylo to people before relevant aDNA
quote:

If A is Modern Africans B is Mena (Modern) and C is every other Modern Eurasian, can we still consider AB Eurasian??
we know B and C will undoubtedly be closer today.
 -
Black lines are drift, red lines are admixture and X represents a single or multiple EARLY population offshoots.....

Now look where we're at... posted on Anthrogenica

...smh lol I need to make a check list of things we're gonna see as we unveil more aDNA.

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@Elmaestro

I like this graph from that anthrogenica link.
https://anthrogenica.com/attachment.php?attachmentid=24022&d=1529080224

I see you guys moved to Anthrogenica and bushed FBD.

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Modern Maghrebis seem to have 20-40% of this IAM/Taf component.

https://image.ibb.co/emtLvJ/Fregel_S77.jpg

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quote:
Originally posted by Elite Diasporan:
@Elmaestro

I like this graph from that anthrogenica link.
https://anthrogenica.com/attachment.php?attachmentid=24022&d=1529080224

I see you guys moved to Anthrogenica and bushed FBD.

It's basically a less nuanced version of what I've been trying to propose for months...if not years elsewhere.

FBD is a dubb... I'm only passing through Anthrogenica tbh. Compare results w/ other people running stats.

I'm discovering a lot of wild shit on my own.

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Xyyman, If you've figured out a way to genotype STR Go ahead and do IAM_5... that sample has a handful of reads viable for CODIS.
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Tukuler
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Please list the AmpFLSTR values.

Fregel's 18 Inner Africans with significant yellow (≥3%).
 -

Not shown:
2 have no yellow, Biaka and Botswana Bantu Kgalagadi speakers.
All her remaining 17 Inner Africans have it, no matter how little.

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BrandonP
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Sorry for being late to the party. I haven't been able to access the full text of the paper, so I'm thankful to everyone who has posted quotes and images in this thread.
quote:
Originally posted by Elmaestro:
 -

Anyone remember when that boy Polako(ithink thats how you spell it) Said the taf was replaced by the IAM who are incoming neolithic population from the Near east lmaooo..

The finding that early Neolithic Moroccans (as represented by IAM) show mostly continuity with Taforalt (including the sizable SSA component) does put a damper on the Eurocentric scenario that Neolithic North Africans were primarily descended from a wave of Near Eastern back-migrants, doesn't it?

That said, I personally think it's a shame that the recent aDNA from Abusir el-Meleq hasn't been incorporated into a study like this. It would be nice to compare those samples with IAM and Taforalt, especially since the latter two seem to be the best proxies we have for ancient North African ancestry.

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Elmaestro
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I posted DL links for the study above, if you still need access.

Now I don’t know what this means yet but Abusir mummies Structurally looks Identical to Levant_BA samples w/ Taforalt involved... infact they’re almost indistinguishable via fst as well (Value of 0). So if you want to know how they look ahead of time just look at levant_BA w/ very slightly less green and more yellow.

Not to get too deep w/ Abusir mummies but though they appear close to levant_BA they might have different population histories... Dstats tends to favor a model where they have ancestry from Minoan Odigitria.. not to mention their anomalous SSA affinity, which makes them appear closer to EEF(especially the Aegean pops) and Levant_N when using an african(ex: mbuti) as an outgtoup.

But as far as ADMIXTURE goes they’ll probably still resemble Levant_BA with IAM involved.

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Tukuler
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Compare Loosdrecht's PCA, with PC1 flipped, to Fregel.
 -
Radar ID
 -
quote:
Fregel's HOD PCA S6.3 plots
• Taforalt closer to SSA than to Natufian
• Natufian overlaying Neolithic Iran
• Neolithic Iran overlayed by KEB
• Taforalt closer to Luxmanda than to Natufian
• Pemba 3X farther from Taforalt than Luxmanda is.

Consider the relative worth of PCA vs other analytic tools.

.

HELP, is South_Africa_12000BP a misprint?

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^@Tukuler yeah it is, remove one 0 the south African is only ~3,200 years old.
Also, I just realized your response to the genetic distance thing.
I want you to know that my initial concern was that YRI are closer to Natufians than they are Taforalt.
Taforalt actually are almost equidistant to YRI and Natufians (more close to YRI). just a FYI


A quick update... cuz I have no life right now.

Above I expressed how Taforalt made good curves as an ancestor to Yorubans.... To anyone who cares, Guess what?

...IAM succeeds and actually produces the best result as an ancestor to YRI against the Bantu-like Pemba individual.

RESULTS

^What's also interesting is the second admixture event (blue highlight) dated around 900ya, I couldn't confidently say how this event makes sense.

right now my best guess that some of the Yoruba have ancestry from a Nomadic Africans and Iberians have respectable YRI-like(with RHG) admixture.

aDNA from Africa is game changing.... The Fst scores from fregel et al actually makes sense.

-- -- -- --

EDIT: Iberia_EN has multiple waves of African Admixture including Mbuti/RHG and YRI seems to have an unspecified Affinity to KEB. Sadly being that these Iberians are ancient the dates for admixture aren't reliably significant... but the generations are to be calculated in respects to the age of the tested populations, the ancient Iberians are like ~7,000ya so the mean date for the earliest Admixture date is ~8380ya.

See Results here

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xyyman
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Come on man!!! Don’t keep us in suspense. If you have the reads..post it or send/PM me.

So you pulled STR from the BAM files of IAM_5?! NIIIICEEEE!!!!


EDIT: Props to Elmaestro!!! Excellent work! Just following up on this thread. Again. Thanks your girlfriend for giving you the time. ("you don't have a life") [Big Grin]

quote:
Originally posted by Elmaestro:
Xyyman, If you've figured out a way to genotype STR Go ahead and do IAM_5... that sample has a handful of reads viable for CODIS.



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xyyman
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@ myman. I need permission to see the results?

"EDIT: Iberia_EN has multiple waves of African Admixture including Mbuti/RHG and YRI seems to have an unspecified Affinity to KEB. Sadly being that these Iberians are ancient the dates for admixture aren't reliably significant... but the generations are to be calculated in respects to the age of the tested populations, the ancient Iberians are like ~7,000ya so the mean date for the earliest Admixture date is ~8380ya.

See Results here"

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Elmaestro
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Updated the link, my apologies.

In regards to the IAM str's I only looked at the CODIS regions manually and seen the sequences. I din't genotype them or pulled any reads. I was kinda hoping I didn't have to be the one who had to.

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Tukuler
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quote:
Originally posted by Tukuler:
Please list the AmpFLSTR values.

Even just the 8 MiniFiler values will do.

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Authentic Africana over race-serving ethnocentricisms, Afro, Euro, or whatever.

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